Motif ID: HOX{A5,B5}.p2

Z-value: 1.203


Transcription factors associated with HOX{A5,B5}.p2:

Gene SymbolEntrez IDGene Name
HOXA5 3202 homeobox A5
HOXB5 3215 homeobox B5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXB5chr17_-_46671043-0.695.7e-02Click!
HOXA5chr7_-_271832250.373.7e-01Click!


Activity profile for motif HOX{A5,B5}.p2.

activity profile for motif HOX{A5,B5}.p2


Sorted Z-values histogram for motif HOX{A5,B5}.p2

Sorted Z-values for motif HOX{A5,B5}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A5,B5}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_2019007 0.869 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr3_-_121379757 0.777 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr15_+_74218811 0.628 LOXL1
lysyl oxidase-like 1
chr15_+_74218794 0.611 LOXL1
lysyl oxidase-like 1
chr15_+_74218786 0.608 NM_005576
LOXL1
lysyl oxidase-like 1
chr8_-_93107881 0.608 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr2_+_17721806 0.570 NM_003385
VSNL1
visinin-like 1
chr11_-_2018446 0.530 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr11_-_2018334 0.494 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr8_-_93107442 0.492 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr11_-_111782447 0.485 NM_001885
CRYAB
crystallin, alpha B
chr2_+_17721983 0.426 VSNL1
visinin-like 1
chr8_-_93107643 0.410 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_+_135230736 0.400 NM_001159700
FHL1
four and a half LIM domains 1
chr12_-_6484904 0.392 NM_001038
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr19_+_51152634 0.383 NM_001195076
C19orf81
chromosome 19 open reading frame 81
chr12_-_53614121 0.378 NM_001042728
NM_001243732
RARG

retinoic acid receptor, gamma

chr6_+_121756744 0.374 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr2_+_30369868 0.367 YPEL5
yippee-like 5 (Drosophila)
chr11_-_2018568 0.367 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr11_-_2018885 0.336 H19
RPS12
H19, imprinted maternally expressed transcript (non-protein coding)
ribosomal protein S12
chr1_+_153003677 0.321 NM_003125
SPRR1B
small proline-rich protein 1B
chr6_+_31543340 0.317 NM_000594
TNF
tumor necrosis factor
chr13_-_114018201 0.316 GRTP1
growth hormone regulated TBC protein 1
chrX_+_99899388 0.314 SRPX2
sushi-repeat containing protein, X-linked 2
chr17_-_46894380 0.297 NM_001130918
TTLL6
tubulin tyrosine ligase-like family, member 6
chr1_-_155177685 0.296 NM_001252607
NM_001252608
NM_007112
THBS3


thrombospondin 3


chr12_-_56101465 0.290 ITGA7
integrin, alpha 7
chr19_-_49567123 0.288 NM_006179
NTF4
neurotrophin 4
chr2_+_30369800 0.273 YPEL5
yippee-like 5 (Drosophila)
chr1_+_35220647 0.270 NM_005268
GJB5
gap junction protein, beta 5, 31.1kDa
chr1_+_24645811 0.268 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr10_-_14646407 0.267 FAM107B
family with sequence similarity 107, member B
chr19_+_8117887 0.266 CCL25
chemokine (C-C motif) ligand 25
chr1_+_150245182 0.258 NM_024579
C1orf54
chromosome 1 open reading frame 54
chr21_-_28339405 0.252 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr17_-_7166505 0.251 NM_001185022
CLDN7
claudin 7
chr12_+_54955226 0.250 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr2_+_30369749 0.250 NM_001127399
NM_001127400
NM_001127401
NM_016061
YPEL5



yippee-like 5 (Drosophila)



chr5_+_133842276 0.246


chr1_-_161008733 0.244 NM_001113205
NM_001113206
NM_001113207
TSTD1


F11R
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1


F11 receptor
chr1_+_24645914 0.238 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr9_+_117904096 0.230 NM_017418
DEC1
deleted in esophageal cancer 1
chr11_+_36317724 0.227 NM_001160167
PRR5L
proline rich 5 like
chr6_+_36644236 0.226 NM_001220777
NM_078467
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr22_-_36556781 0.225 NM_145640
APOL3
apolipoprotein L, 3
chr9_+_42717233 0.220 NM_001099279
NM_199244
FOXD4L2
FOXD4L4
forkhead box D4-like 2
forkhead box D4-like 4
chr4_+_41258909 0.219 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr1_-_155948934 0.218 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr20_-_50418946 0.213 NM_020436
SALL4
sal-like 4 (Drosophila)
chr19_-_47922339 0.211 MEIS3
Meis homeobox 3
chr11_-_2018703 0.211 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr16_-_84651639 0.206 NM_021149
COTL1
coactosin-like 1 (Dictyostelium)
chr1_-_144994908 0.203 PDE4DIP
phosphodiesterase 4D interacting protein
chr12_-_106533810 0.202 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr1_-_144994943 0.202 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chrX_+_151084708 0.202 NM_002362
MAGEA4
melanoma antigen family A, 4
chr4_+_41258895 0.202 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr4_+_15480833 0.201 CC2D2A
coiled-coil and C2 domain containing 2A
chr1_+_111413820 0.199 NM_001040033
CD53
CD53 molecule
chr2_-_56151273 0.196 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr19_-_46405854 0.189 NM_001012643
MYPOP
Myb-related transcription factor, partner of profilin
chr20_+_12989616 0.189 NM_018327
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr10_+_75673346 0.187 PLAU
plasminogen activator, urokinase
chr9_-_86571652 0.187 NM_032307
C9orf64
chromosome 9 open reading frame 64
chr19_-_52227220 0.186 NM_001523
HAS1
hyaluronan synthase 1
chr16_+_3115641 0.186 NM_001012632
NM_001012636
IL32

interleukin 32

chr6_-_97285058 0.184 NM_001143957
NM_030784
GPR63

G protein-coupled receptor 63

chr11_+_5617864 0.180 NM_001003818
NM_001198644
NM_001198645
NM_001003819
TRIM6


TRIM6-TRIM34
tripartite motif containing 6


TRIM6-TRIM34 readthrough
chr17_+_7284292 0.177 NM_001251902
NM_003985
TNK1

tyrosine kinase, non-receptor, 1

chr1_+_82266081 0.175 NM_012302
LPHN2
latrophilin 2
chr2_-_211179765 0.172 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr9_-_70429730 0.172 NM_001099279
NM_199244
FOXD4L2
FOXD4L4
forkhead box D4-like 2
forkhead box D4-like 4
chr2_-_113542970 0.171 NM_000575
IL1A
interleukin 1, alpha
chr9_-_70178814 0.168 NM_001126334
FOXD4L5
forkhead box D4-like 5
chr17_-_72542148 0.167 CD300C
CD300c molecule
chr7_+_26331611 0.167 SNX10
sorting nexin 10
chr17_-_5404304 0.165 NM_001162371
LOC728392
uncharacterized LOC728392
chr1_+_16085245 0.165 NM_017556
FBLIM1
filamin binding LIM protein 1
chr19_-_51845377 0.164 NM_001163922
VSIG10L
V-set and immunoglobulin domain containing 10 like
chr4_+_41258941 0.163 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr1_-_36851484 0.162 NM_032017
STK40
serine/threonine kinase 40
chr12_+_7013896 0.161 NM_001135217
NM_006992
NM_201650
LRRC23


leucine rich repeat containing 23


chr1_-_160990862 0.160 F11R
F11 receptor
chr1_+_86889768 0.158 NM_006536
CLCA2
chloride channel accessory 2
chr1_-_36851517 0.158 STK40
serine/threonine kinase 40
chr1_-_28503454 0.157 NM_000952
NM_001164723
PTAFR

platelet-activating factor receptor

chr19_+_8117645 0.157 NM_001201359
NM_005624
CCL25

chemokine (C-C motif) ligand 25

chr1_-_144994839 0.157 PDE4DIP
phosphodiesterase 4D interacting protein
chr16_-_1821503 0.156 NME3
non-metastatic cells 3, protein expressed in
chrX_+_99899162 0.154 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr5_+_149569519 0.154 NM_014228
SLC6A7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr3_-_55521330 0.153 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr2_+_42795844 0.151 MTA3
metastasis associated 1 family, member 3
chr9_-_28719302 0.151 NM_152570
LINGO2
leucine rich repeat and Ig domain containing 2
chr17_-_38657814 0.149 NM_032865
TNS4
tensin 4
chr10_+_102295700 0.149 HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr12_-_52845862 0.149 NM_005555
KRT6B
keratin 6B
chr4_-_110723334 0.148 NM_000204
CFI
complement factor I
chr4_+_30722445 0.144 PCDH7
protocadherin 7
chr19_-_2015628 0.141 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr6_+_146056007 0.140 LOC100507557
uncharacterized LOC100507557
chrX_-_107225588 0.140 NM_031273
TEX13B
testis expressed 13B
chr16_+_57662301 0.140 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr2_+_42795601 0.138 NM_020744
MTA3
metastasis associated 1 family, member 3
chr1_+_28585959 0.137 NM_031459
SESN2
sestrin 2
chr6_+_125475334 0.137 NM_001003395
TPD52L1
tumor protein D52-like 1
chr12_-_7818467 0.137 NM_001644
APOBEC1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr9_+_35673852 0.136 NM_001216
CA9
carbonic anhydrase IX
chrX_-_64196268 0.135 NM_001178033
NM_018684
ZC4H2

zinc finger, C4H2 domain containing

chr18_-_52969714 0.133 NM_001243236
TCF4
transcription factor 4
chr16_-_1821709 0.133 NM_002513
NME3
non-metastatic cells 3, protein expressed in
chr19_+_50354417 0.132 PTOV1
prostate tumor overexpressed 1
chr17_-_48271968 0.131


chr16_-_2031179 0.131 NM_172167
NM_172168
NOXO1

NADPH oxidase organizer 1

chr2_-_220173693 0.130 NM_001199764
PTPRN
protein tyrosine phosphatase, receptor type, N
chr14_+_21236585 0.127 NM_022360
EDDM3B
epididymal protein 3B
chr19_-_14064192 0.127 NM_001146254
NM_001146255
PODNL1

podocan-like 1

chr4_-_138453628 0.123 NM_019035
PCDH18
protocadherin 18
chr1_-_160990971 0.122 NM_016946
F11R
F11 receptor
chr4_-_100242487 0.122 NM_000668
ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr11_-_125648704 0.121 NM_212555
PATE2
prostate and testis expressed 2
chrX_+_151086708 0.121 NM_001011550
MAGEA4
melanoma antigen family A, 4
chrX_+_79675945 0.121 NM_152630
FAM46D
family with sequence similarity 46, member D
chr10_-_14646237 0.120 FAM107B
family with sequence similarity 107, member B
chr1_+_209602164 0.120 NM_001104548
MIR205HG
MIR205 host gene (non-protein coding)
chr19_+_34745452 0.119 NM_014686
KIAA0355
KIAA0355
chrX_+_151085396 0.119 NM_001011549
MAGEA4
melanoma antigen family A, 4
chr19_-_50143350 0.118 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr5_-_149535138 0.117 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr6_+_30856462 0.117 NM_001202521
NM_001202522
NM_013994
DDR1


discoidin domain receptor tyrosine kinase 1


chr5_+_55147206 0.115 NM_001242637
NM_001242638
NM_139017
IL31RA


interleukin 31 receptor A


chr6_-_31514620 0.115 NM_001204078
NM_130463
NM_138282
ATP6V1G2


ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2


chr12_-_6484389 0.114 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr1_-_89591685 0.113 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr1_-_153600714 0.113 NM_005979
S100A13
S100 calcium binding protein A13
chr3_+_49208979 0.112 NM_173546
KLHDC8B
kelch domain containing 8B
chr14_+_68086633 0.111 ARG2
arginase, type II
chr19_+_5823817 0.111 NM_004558
NRTN
neurturin
chr12_+_7167979 0.111 NM_001734
NM_201442
C1S

complement component 1, s subcomponent

chr1_-_23810627 0.111 ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr12_-_6798528 0.110 NM_133476
ZNF384
zinc finger protein 384
chr12_-_6798419 0.110 ZNF384
zinc finger protein 384
chr19_+_46367517 0.110 NM_004497
FOXA3
forkhead box A3
chr6_-_10419786 0.108 NM_001042425
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_+_6679551 0.107 NM_153230
FBXO39
F-box protein 39
chr20_+_3024267 0.106 NM_001501
NM_178331
NM_178332
GNRH2


gonadotropin-releasing hormone 2


chr17_+_7338761 0.106 NM_178518
TMEM102
transmembrane protein 102
chr22_-_41636855 0.105 NM_138481
CHADL
chondroadherin-like
chr1_+_198608244 0.105 PTPRC
protein tyrosine phosphatase, receptor type, C
chr8_+_21916858 0.104 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr11_+_12308446 0.100 NM_032867
MICALCL
MICAL C-terminal like
chr7_-_98030165 0.099 BAIAP2L1
BAI1-associated protein 2-like 1
chr17_-_40337384 0.099 NM_001524
HCRT
hypocretin (orexin) neuropeptide precursor
chr12_-_6484557 0.099 SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr2_-_85637473 0.098 CAPG
capping protein (actin filament), gelsolin-like
chr2_-_70780621 0.098 TGFA
transforming growth factor, alpha
chr19_-_16008870 0.098 NM_001082
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chr10_+_91152321 0.097 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr1_-_153599969 0.097 NM_001024211
S100A13
S100 calcium binding protein A13
chr6_+_155585146 0.097 NM_001001346
CLDN20
claudin 20
chr4_-_84255999 0.097 HPSE
heparanase
chr22_-_37584254 0.097 NM_031910
NM_182486
C1QTNF6

C1q and tumor necrosis factor related protein 6

chr8_+_132991171 0.096 EFR3A
EFR3 homolog A (S. cerevisiae)
chr7_+_26331493 0.096 NM_001199835
NM_013322
SNX10

sorting nexin 10

chr9_+_70917782 0.096 NM_199135
FOXD4L3
FOXD4L6
forkhead box D4-like 3
forkhead box D4-like 6
chr8_+_21916685 0.096 NM_001114138
NM_001978
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr6_-_42162693 0.095 NM_002098
GUCA1B
guanylate cyclase activator 1B (retina)
chr11_-_114271052 0.094 NM_019021
C11orf71
chromosome 11 open reading frame 71
chr9_+_135937364 0.094 NM_001807
CEL
carboxyl ester lipase (bile salt-stimulated lipase)
chr14_+_68086655 0.093 ARG2
arginase, type II
chr7_-_107880492 0.093 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr19_-_291168 0.091 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr2_-_85637486 0.091 NM_001747
CAPG
capping protein (actin filament), gelsolin-like
chr17_+_38230678 0.090 THRA
thyroid hormone receptor, alpha
chr5_-_158526698 0.090 NM_024007
EBF1
early B-cell factor 1
chr19_-_44306525 0.090 NM_001031749
LYPD5
LY6/PLAUR domain containing 5
chr11_+_10472223 0.090 NM_000480
AMPD3
adenosine monophosphate deaminase 3
chr16_-_50402685 0.088 NM_001173984
NM_013263
BRD7

bromodomain containing 7

chr13_-_114018365 0.088 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr20_-_42816217 0.088 NM_020433
NM_175913
JPH2

junctophilin 2

chr11_+_126275947 0.087 ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr17_-_72542244 0.086 NM_006678
CD300C
CD300c molecule
chr12_+_7282963 0.086 NM_014718
CLSTN3
calsyntenin 3
chr17_-_48271365 0.086


chr2_+_75185765 0.086 NM_019896
POLE4
polymerase (DNA-directed), epsilon 4 (p12 subunit)
chr4_-_25864430 0.085 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr4_-_76944585 0.085 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr3_-_196065243 0.084 NM_001204897
NM_001204898
NM_138461
TM4SF19


transmembrane 4 L six family member 19


chr4_-_84255895 0.084 NM_001199830
HPSE
heparanase
chr4_-_48014960 0.083 NM_000087
CNGA1
cyclic nucleotide gated channel alpha 1
chr4_+_144257982 0.083 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr16_-_57570455 0.083 NM_033212
CCDC102A
coiled-coil domain containing 102A
chr2_+_113931565 0.082 PSD4
pleckstrin and Sec7 domain containing 4
chr6_+_90604185 0.082 NM_032602
GJA10
gap junction protein, alpha 10, 62kDa
chr10_-_45474210 0.081 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr4_-_46125929 0.080 NM_173536
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chrX_-_55057408 0.079 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr11_+_114271372 0.079 NM_016090
RBM7
RNA binding motif protein 7
chr6_-_33714681 0.078 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.65 1.20e-03 GO:0002376 immune system process
14.09 1.28e-03 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
12.52 3.67e-03 GO:0048880 sensory system development
12.52 3.67e-03 GO:0048892 lateral line nerve development
12.52 3.67e-03 GO:0048895 lateral line nerve glial cell differentiation
12.52 3.67e-03 GO:0048925 lateral line system development
12.52 3.67e-03 GO:0048937 lateral line nerve glial cell development
12.52 3.67e-03 GO:0050935 iridophore differentiation
1.82 4.03e-03 GO:0006955 immune response
1.17 1.43e-02 GO:0065007 biological regulation
10.25 1.84e-02 GO:0060600 dichotomous subdivision of an epithelial terminal unit
1.70 3.16e-02 GO:0006952 defense response
9.39 3.51e-02 GO:0048846 axon extension involved in axon guidance
9.39 3.51e-02 GO:0090184 positive regulation of kidney development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.35 3.29e-02 GO:0044459 plasma membrane part
1.35 4.93e-02 GO:0005576 extracellular region

Nothing significant found in function category.